Patients with cancer cells near their windpipe, in their central nervous system, or in their lungs may need treatment with a glucocorticoid (a medication to help prevent an increase in the size of the cancer cells before using Thyrogen.)
Leftover thyroid tissue after surgery and cancer cells that have spread to other parts of the body can quickly grow and become painful after Thyrogen administration.Patients should remain hydrated prior to treatment with Thyrogen. The relationship between THYROGEN administration and stroke is unknown.
Since Thyrogen was first approved for use, there have been reports of central nervous system problems such as stroke in young women who have a higher chance of having a stroke, and weakness on one side of the body. Thyrogen can be administered in the hospital for patients at risk for complications from Thyrogen administration. Patients over 65 years old with large amounts of leftover thyroid tissue after surgery, or with a history of heart disease, should discuss with their physicians the risks and benefits of Thyrogen. There have been reports of events that led to death in patients who have not had surgery to have their thyroid gland removed, and in patients with thyroid cancer cells that have spread to other parts of the body. Thyrogen can cause serious side effects, including: Please consult with your doctor for a list of contraindications for radioiodine. 
Patients should not use Thyrogen with radioiodine if they have a contraindication to the use of radioiodine.
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